To accommodate users with cognitive disabilities in GUI design:

1. Simple and consistent navigation: Use clear, consistent, and simple navigation patterns.

2. Clear and concise language: Use easy-to-understand language and avoid jargon.

3. Visual hierarchy: Organize content using size, color, and position to create a clear visual hierarchy.

4. Minimal cognitive load: Minimize the amount of information and decisions required from the user.

5. Error prevention and recovery: Anticipate and prevent errors, and provide clear recovery options.

6. Consistency and predictability: Establish consistent design patterns and behaviors.

7. Flexibility and customization: Offer options for users to customize the GUI to suit their needs.

8. Clear and intuitive icons: Use icons that are easily understandable and consistent.

9. Avoid overwhelming content: Break down complex content into smaller, manageable chunks.

10. User testing: Conduct usability testing with users with cognitive disabilities to identify and address issues.

Additionally, consider:

- Using clear and simple imagery

- Providing summaries and abstracts for complex content

- Offering help and support resources

- Using ARIA attributes for screen reader support

- Implementing a "simple mode" or "easy read" option

By incorporating these strategies, you can create a GUI that is more accessible and usable for users with cognitive disabilities.