User-centered design (UCD) in GUIs focuses on creating interfaces that are intuitive, easy to use, and meet the needs of the target audience. It involves:

1. Understanding user goals, behaviors, and motivations

2. Empathizing with users through research and testing

3. Designing interfaces that are clear, consistent, and intuitive

4. Involving users in the design process through feedback and iteration

5. Prioritizing user needs and abilities

6. Creating interfaces that are flexible and adaptable

7. Continuously testing and refining the design

UCD principles in GUIs aim to:

1. Reduce cognitive load

2. Minimize errors

3. Increase efficiency

4. Enhance user satisfaction

5. Improve accessibility

By applying UCD principles, GUI designers can create interfaces that are tailored to the needs of their users, resulting in a more positive and productive user experience.